Drug profile

The FDA adverse-event record for Topical Flea Product

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Topical Flea Product. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
6.7%
death-coded share
Dog
most-reported species
7
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
1
Deaths Reported
6.7%
Death Rate

Active Ingredients

Topical Flea Product

Administration Routes

TopicalUnknown

Species Affected

Dog 11
Cat 4

Most Affected Breeds

Shepherd Dog - Australian 5
Domestic Shorthair 3
Chow Chow 1
Shih Tzu 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Domestic Longhair 1
Doberman Pinscher 1
Crossbred Canine/dog 1
Terrier - Yorkshire 1

Most Reported Reactions

Lack of efficacy - NOS 7
Lack of efficacy (ectoparasite) - flea 7
Panting 3
Deafness 1
Excessive licking and/or grooming 1
Trembling 1
Skin sore 1
Alopecia 1
Skin scab 1
Fever 1
Reduced responses 1
Lateral recumbency 1

Outcome Breakdown

Ongoing
8 (57.1%)
Outcome Unknown
4 (28.6%)
Recovered/Normal
1 (7.1%)
Died
1 (7.1%)

Topical Flea Product Adverse Event Insights

15 reports name Topical Flea Product; 1 recorded a death outcome (6.7% of reported events, not a population-level mortality rate). Active ingredient: Topical Flea Product. Administration routes: Topical, Unknown.

By species: Dog (11 reports), Cat (4 reports). By breed: Shepherd Dog - Australian (5), Domestic Shorthair (3), Chow Chow (1).

Leading clinical signs: Lack of efficacy - NOS (7), Lack of efficacy (ectoparasite) - flea (7), Panting (3), Deafness (1). Outcome, 14 coded reports: Ongoing leads at 57.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.