Drug profile

The FDA adverse-event record for Tick Treatment (Unknown)

41 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Tick Treatment (Unknown). Species, reactions, and outcomes follow.

#1242 of 2,679
by report volume (all drugs)
41
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Tick Treatment (Unknown) ranks #1235 of 2679 by total reports (41). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1235
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tick Treatment (Unknown) has 41 reports now versus 41 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tick Treatment (Unknown) changes

Signature read: Tick Treatment (Unknown)'s 0.0% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
41
Total Reports
0
Deaths Reported
0.0%
Death-coded share of reports

Active Ingredients

Tick Treatment (Unknown)

Administration Routes

UnknownTopicalOral

Species Affected

Dog 41

Most Affected Breeds

Retriever - Golden 5
Maltese 4
Retriever - Labrador 4
Terrier - Yorkshire 3
Beagle 3
Dog (other) 2
Schnauzer (unspecified) 2
Shepherd Dog - German 2
Crossbred Canine/dog 2
Shih Tzu 2

Most Reported Reactions

Emesis 11
Vomiting 10
Lethargy (see also Central nervous system depression in 'Neurological') 4
Other abnormal test result NOS 4
Not eating 3
Diarrhoea 3
Lack of efficacy - NOS 3
Lack of efficacy (endoparasite) - hookworm 3
INEFFECTIVE, HOOKS 3
Disorientation 2
Behavioural disorder NOS 2
Decreased appetite 2

Outcome Breakdown

Recovered/Normal
26 (63.4%)
Outcome Unknown
9 (22.0%)
Recovered with Sequela
4 (9.8%)
Ongoing
2 (4.9%)

Tick Treatment (Unknown): low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tick Treatment (Unknown) (#1242 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →