Drug profile

The FDA adverse-event record for Thiamine

10 FDA reports name Thiamine, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2651 of 2,679
by report volume (all drugs)
10
adverse-event reports
80.0%
death-coded share
Cat
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Thiamine ranks #2536 of 2679 by total reports (10). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2536
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: Thiamine's 80.0% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
8
Deaths Reported
80.0%
Death-coded share of reports

Active Ingredients

Thiamine

Administration Routes

UnknownIntravenous

Species Affected

Cat 4
Cattle 3
Goat 1
Alpaca 1
Dog 1

Most Affected Breeds

Cattle (other) 2
Domestic Shorthair 2
Nubian 1
Red Angus 1
Domestic Mediumhair 1
Alpaca 1
Spitz - German Pomeranian 1
Domestic Longhair 1

Most Reported Reactions

Death 7
Behavioural disorder NOS 3
Anaemia NOS 3
Mydriasis 3
Ptyalism 3
Other abnormal test result NOS 3
Abnormal breathing 2
Lack of efficacy (bacteria) - NOS 2
Lateral recumbency 2
Lack of efficacy - NOS 2
Congestive heart failure 2
Not eating 2

Outcome Breakdown

Died
7 (53.8%)
Ongoing
2 (15.4%)
Outcome Unknown
2 (15.4%)
Recovered/Normal
1 (7.7%)
Euthanized
1 (7.7%)

Thiamine: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thiamine (#2651 of 2,679 by report volume); death-coded 80.0%. PlainBreed drug row · death-coded share stamp 80.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →