Drug profile

The FDA adverse-event record for Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass)

10 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass). See the species affected, top reactions, and outcomes below.

10
adverse-event reports
30.0%
death-coded share
Cattle
most-reported species
4
No sign - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
3
Deaths Reported
30.0%
Death Rate

Active Ingredients

Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass)

Administration Routes

OralUnknown

Species Affected

Cattle 8
Horse 1
Unknown 1

Most Affected Breeds

Holstein-Friesian also known as Holstein 3
Cattle (other) 3
Jersey 1
Quarter Horse 1
Unknown 1
Mixed (Cattle) 1

Most Reported Reactions

No sign 4
Lack of efficacy (bacteria) - NOS 2
Increased mortality rate 1
Death by euthanasia 1
NT - Abnormal necropsy finding NOS 1
Abscess NOS 1
Pulmonary disorder NOS 1
Lack of efficacy (protozoa) - Coccidia 1
Containers, Damaged 1
Closure, Abnormal 1
Diarrhoea 1
Respiratory tract infection NOS 1

Outcome Breakdown

Outcome Unknown
7 (53.8%)
Died
3 (23.1%)
Ongoing
2 (15.4%)
Euthanized
1 (7.7%)

Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass) Adverse Event Insights

10 reports name Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass); 3 recorded a death outcome (30.0% of reported events, not a population-level mortality rate). Active ingredient: Sulfamethazine; Chlortetracycline As Calcium Complex (Biomass). Administration routes: Oral, Unknown.

By species: Cattle (8 reports), Horse (1 reports), Unknown (1 reports). By breed: Holstein-Friesian also known as Holstein (3), Cattle (other) (3), Jersey (1).

Leading clinical signs: No sign (4), Lack of efficacy (bacteria) - NOS (2), Increased mortality rate (1), Death by euthanasia (1). Outcome, 13 coded reports: Outcome Unknown leads at 53.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.