Drug profile

The FDA adverse-event record for Sulfamethazine

35 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Sulfamethazine. See the species affected, top reactions, and outcomes below.

35
adverse-event reports
28.6%
death-coded share
Unknown
most-reported species
9
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
35
Total Reports
10
Deaths Reported
28.6%
Death Rate

Active Ingredients

Sulfamethazine

Administration Routes

UnknownOral

Species Affected

Unknown 18
Chicken 5
Cattle 5
Other Birds 4
Goat 1
Human 1
Dog 1

Most Affected Breeds

Unknown 19
Chicken (unknown) 4
Other Birds (unknown) 4
Mixed (Cattle) 2
Crossbred Caprine/goat 1
Retriever - Labrador 1
Holstein-Friesian also known as Holstein 1
Jersey 1
Red Angus 1
Leghorn 1

Most Reported Reactions

Death 9
Color, Abnormal 3
Vials, Leaking 3
Solution, Abnormal 2
Product Defect, General 2
Caps, Abnormal 2
Respiratory distress 2
Diarrhoea 1
Lack of efficacy (protozoa) - Coccidia 1
Granules/Powder, Abnormal 1
UNPALATABLE 1
Containers, Damaged 1

Outcome Breakdown

Died
9 (50.0%)
Recovered/Normal
4 (22.2%)
Outcome Unknown
3 (16.7%)
Recovered with Sequela
1 (5.6%)
Euthanized
1 (5.6%)

Sulfamethazine Adverse Event Insights

35 reports name Sulfamethazine; 10 recorded a death outcome (28.6% of reported events, not a population-level mortality rate). Active ingredient: Sulfamethazine. Administration routes: Unknown, Oral.

By species: Unknown (18 reports), Chicken (5 reports), Cattle (5 reports). By breed: Unknown (19), Chicken (unknown) (4), Other Birds (unknown) (4).

Leading clinical signs: Death (9), Color, Abnormal (3), Vials, Leaking (3), Solution, Abnormal (2). Outcome, 18 coded reports: Died leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.