S-Adenosylmethionine/Silybin-Phosphatidylcholine Complex
44 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
44
Total Reports
5
Deaths Reported
1140.0%
Death Rate
Active Ingredients
S-Adenosylmethionine/Silybin-Phosphatidylcholine Complex
Administration Routes
OralUnknown
Species Affected
Dog 37
Cat 7
Most Affected Breeds
Domestic Shorthair 6
Retriever - Labrador 5
Maltese 3
Crossbred Canine/dog 3
Schnauzer (unspecified) 3
Great Pyrenees 2
Retriever - Golden 2
Dog (unknown) 2
Terrier - Boston 2
Domestic Longhair 1
Most Reported Reactions
Elevated alanine aminotransferase (ALT) 17
Elevated total bilirubin 10
Vomiting 8
Elevated serum alkaline phosphatase (SAP) 8
Lethargy (see also Central nervous system depression in 'Neurological') 7
Elevated creatinine 7
Weight loss 7
Elevated gamma-glutamyl transferase (GGT) 6
Diarrhoea 6
Behavioural disorder NOS 5
Anorexia 5
Lethargy (see also Central nervous system depression in Neurological) 5
Outcome Breakdown
Outcome Unknown
20 (45.5%)
Recovered/Normal
10 (22.7%)
Ongoing
9 (20.5%)
Died
4 (9.1%)
Euthanized
1 (2.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.