Drug profile

The FDA adverse-event record for Rabies Virus Vaccine

21 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Rabies Virus Vaccine. See the species affected, top reactions, and outcomes below.

21
adverse-event reports
9.5%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
21
Total Reports
2
Deaths Reported
9.5%
Death Rate

Active Ingredients

Rabies Virus Vaccine

Administration Routes

UnknownSubcutaneousParenteral

Species Affected

Dog 17
Cat 4

Most Affected Breeds

Domestic Shorthair 3
Shih Tzu 2
Pit Bull 2
Retriever - Labrador 2
Griffon (unspecified) 2
Schnauzer - Miniature 1
Terrier (unspecified) 1
Terrier - Yorkshire 1
Crossbred Canine/dog 1
Great Pyrenees 1

Most Reported Reactions

Vomiting 5
Lack of efficacy (endoparasite) - heartworm 4
Diarrhoea 3
Monocytosis 3
Basophilia 3
Low serum alkaline phosphatase (ALP) 3
Low platelet count 3
Drooling 2
Fever 2
Other abnormal test result NOS 2
Seizure NOS 2
Leucopenia NOS 2

Outcome Breakdown

Outcome Unknown
11 (52.4%)
Ongoing
5 (23.8%)
Recovered/Normal
3 (14.3%)
Euthanized
1 (4.8%)
Died
1 (4.8%)

Rabies Virus Vaccine Adverse Event Insights

21 reports name Rabies Virus Vaccine; 2 recorded a death outcome (9.5% of reported events, not a population-level mortality rate). Active ingredient: Rabies Virus Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral.

By species: Dog (17 reports), Cat (4 reports). By breed: Domestic Shorthair (3), Shih Tzu (2), Pit Bull (2).

Leading clinical signs: Vomiting (5), Lack of efficacy (endoparasite) - heartworm (4), Diarrhoea (3), Monocytosis (3). Outcome, 21 coded reports: Outcome Unknown leads at 52.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.