Drug profile

The FDA adverse-event record for Rabies 1 Year Vaccine

Name: Rabies 1 Year Vaccine - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

14 FDA reports name Rabies 1 Year Vaccine, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2195 of 2,679
by report volume (all drugs): 14
adverse-event reports: 28.6%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Rabies 1 Year Vaccine ranks #2133 of 2679 by total reports (14). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #2133
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Rabies 1 Year Vaccine has 14 reports now versus 10 in that prior snapshot: 4 more (40.0%).

Report change: +4
Death-coded reports: +1
Death-coded share: −1.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Rabies 1 Year Vaccine changes

Signature read: Rabies 1 Year Vaccine's 28.6% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

28.6%

Death-coded share of reports

Active Ingredients

Rabies 1 Year Vaccine

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 10

Cat 4

Most Affected Breeds

Domestic Shorthair 3

Bulldog 1

Dachshund - Miniature 1

Terrier - Bull - American Pit 1

Sphynx 1

Poodle - Miniature 1

Chihuahua 1

Bulldog - American 1

Rottweiler 1

Shepherd Dog - German 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 5

Death 3

Emesis (multiple) 3

Elevated alanine aminotransferase (ALT) 2

Elevated serum alkaline phosphatase (ALP) 2

Elevated total bilirubin 2

Other abnormal test result NOS 1

Application site alopecia 1

Vomiting 1

Lethargy (see also Central nervous system depression in 'Neurological') 1

Tremor 1

Hyperphosphataemia 1

Outcome Breakdown

Ongoing

6 (42.9%)

Died

3 (21.4%)

Outcome Unknown

2 (14.3%)

Recovered/Normal

2 (14.3%)

Euthanized

1 (7.1%)

Rabies 1 Year Vaccine: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Rabies 1 Year Vaccine (#2195 of 2,679 by report volume); death-coded 28.6%. PlainBreed drug row · death-coded share stamp 28.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →