Drug profile

The FDA adverse-event record for Propylene Glycol + Salicylic Acid

28 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Propylene Glycol + Salicylic Acid. See the species affected, top reactions, and outcomes below.

28
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
13
Lack of efficacy - NOS - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
28
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Propylene GlycolPropylene Glycol + Salicylic AcidSalicylic Acid

Administration Routes

Auricular (Otic)Unknown

Species Affected

Dog 28

Most Affected Breeds

Retriever - Labrador 6
Terrier - Yorkshire 3
Pointer (unspecified) 2
Pointing Dog - Hungarian Short-haired (Vizsla) 2
Bulldog 2
Terrier - West Highland White 1
Terrier - Rat 1
Boxer (German Boxer) 1
Bloodhound 1
Pit Bull 1

Most Reported Reactions

Lack of efficacy - NOS 13
Loss of hearing 5
Vomiting 3
Other abnormal test result NOS 2
Ear pain 2
Impaired hearing 2
Deafness 2
Sleepiness - systemic disorder 2
Ear discharge 2
Behavioural disorder NOS 2
Other ear disorder NOS 2
Polyuria 1

Outcome Breakdown

Outcome Unknown
16 (57.1%)
Ongoing
10 (35.7%)
Recovered/Normal
2 (7.1%)

Propylene Glycol + Salicylic Acid Adverse Event Insights

28 reports name Propylene Glycol + Salicylic Acid; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredients: Propylene Glycol, Propylene Glycol + Salicylic Acid, Salicylic Acid. Administration routes: Auricular (Otic), Unknown.

By species: Dog (28 reports). By breed: Retriever - Labrador (6), Terrier - Yorkshire (3), Pointer (unspecified) (2).

Leading clinical signs: Lack of efficacy - NOS (13), Loss of hearing (5), Vomiting (3), Other abnormal test result NOS (2). Outcome, 28 coded reports: Outcome Unknown leads at 57.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.