Drug profile

The FDA adverse-event record for Prednisone 20 Mg

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prednisone 20 Mg. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
6.7%
death-coded share
Dog
most-reported species
4
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
1
Deaths Reported
6.7%
Death Rate

Active Ingredients

Prednisone 20 Mg

Administration Routes

OralUnknown

Species Affected

Dog 15

Most Affected Breeds

Shepherd Dog - German 4
Pointing Dog - Hungarian Short-haired (Vizsla) 2
Deutsche Dogge, Great Dane 1
Retriever - Labrador 1
Terrier - Bull - Staffordshire 1
Crossbred Canine/dog 1
Pit Bull 1
Boxer (German Boxer) 1
Akita 1
Siberian Husky 1

Most Reported Reactions

Vomiting 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Lack of efficacy (endoparasite) - heartworm 3
Elevated alanine aminotransferase (ALT) 3
Tachycardia 2
Increased respiratory rate 2
Bloody diarrhoea 2
Polydipsia 2
Polyuria 2
Discoloured urine 2
Elevated blood urea nitrogen (BUN) 2
Elevated serum alkaline phosphatase (ALP) 2

Outcome Breakdown

Outcome Unknown
8 (53.3%)
Recovered/Normal
5 (33.3%)
Ongoing
1 (6.7%)
Euthanized
1 (6.7%)

Prednisone 20 Mg Adverse Event Insights

15 reports name Prednisone 20 Mg; 1 recorded a death outcome (6.7% of reported events, not a population-level mortality rate). Active ingredient: Prednisone 20 Mg. Administration routes: Oral, Unknown.

By species: Dog (15 reports). By breed: Shepherd Dog - German (4), Pointing Dog - Hungarian Short-haired (Vizsla) (2), Deutsche Dogge, Great Dane (1).

Leading clinical signs: Vomiting (4), Lethargy (see also Central nervous system depression in 'Neurological') (3), Lack of efficacy (endoparasite) - heartworm (3), Elevated alanine aminotransferase (ALT) (3). Outcome, 15 coded reports: Outcome Unknown leads at 53.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.