Drug profile

The FDA adverse-event record for Prednisolone + Trimeprazine

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prednisolone + Trimeprazine. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
3
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

PrednisoloneTrimeprazine

Administration Routes

OralUnknown

Species Affected

Dog 8
Unknown 4

Most Affected Breeds

Unknown 4
Shih Tzu 3
Chihuahua 1
Pug 1
Bichon Frise 1
Terrier (unspecified) 1
Schnauzer - Miniature 1

Most Reported Reactions

Diarrhoea 3
Seizure NOS 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Anorexia 2
Physical label missing 2
Pyoderma 1
General hair loss 1
Crust 1
Bacterial skin infection NOS 1
Skin sore 1
PR-SKIN, LESION(S) 1
CULTURE/TITER DATA ABNORMAL 1

Outcome Breakdown

Ongoing
4 (50.0%)
Recovered/Normal
3 (37.5%)
Outcome Unknown
1 (12.5%)

Prednisolone + Trimeprazine Adverse Event Insights

12 reports name Prednisolone + Trimeprazine; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredients: Prednisolone, Trimeprazine. Administration routes: Oral, Unknown.

By species: Dog (8 reports), Unknown (4 reports). By breed: Unknown (4), Shih Tzu (3), Chihuahua (1).

Leading clinical signs: Diarrhoea (3), Seizure NOS (2), Lethargy (see also Central nervous system depression in 'Neurological') (2), Anorexia (2). Outcome, 8 coded reports: Ongoing leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.