Drug profile

The FDA adverse-event record for Pradofloxacin Trihydrate

Name: Pradofloxacin Trihydrate - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

11 FDA reports name Pradofloxacin Trihydrate, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2493 of 2,679
by report volume (all drugs): 11
adverse-event reports: 45.5%
death-coded share: Cattle
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Pradofloxacin Trihydrate ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: Pradofloxacin Trihydrate's 45.5% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

45.5%

Death-coded share of reports

Active Ingredients

Pradofloxacin Trihydrate

Administration Routes

UnknownParenteralSubcutaneousTransdermal

Species Affected

Cattle 5

Human 3

Unknown 2

Dog 1

Most Affected Breeds

Unknown 5

Cattle (unknown) 3

Hound (unspecified) 1

Cattle (other) 1

Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Death 4

Lack of efficacy - NOS 3

Accidental exposure 3

Injection site bleeding 2

Injection site pain 2

Needlestick injury 2

Containers, Damaged 1

Disorientation 1

Epistaxis 1

Sickness 1

Injection site erythema 1

Injection site swelling 1

Outcome Breakdown

Died

4 (30.8%)

Ongoing

3 (23.1%)

Outcome Unknown

3 (23.1%)

Recovered/Normal

2 (15.4%)

Euthanized

1 (7.7%)

Pradofloxacin Trihydrate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pradofloxacin Trihydrate (#2493 of 2,679 by report volume); death-coded 45.5%. PlainBreed drug row · death-coded share stamp 45.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →