Drug profile

The FDA adverse-event record for Polysulfated Glycosaminoglycan (Psgag)

26 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Polysulfated Glycosaminoglycan (Psgag). Species, reactions, and outcomes follow.

#1566 of 2,679
by report volume (all drugs)
26
adverse-event reports
3.8%
death-coded share
Unknown
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Polysulfated Glycosaminoglycan (Psgag) ranks #1543 of 2679 by total reports (26). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1543
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Polysulfated Glycosaminoglycan (Psgag) has 26 reports now versus 25 in that prior snapshot: 1 more (4.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Polysulfated Glycosaminoglycan (Psgag) changes

Signature read: Polysulfated Glycosaminoglycan (Psgag)'s 3.8% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
26
Total Reports
1
Deaths Reported
3.8%
Death-coded share of reports

Active Ingredients

Polysulfated Glycosaminoglycan (Psgag)

Administration Routes

Unknown

Species Affected

Unknown 18
Dog 8

Most Affected Breeds

Unknown 18
Retriever - Labrador 4
Retriever - Golden 2
Bulldog - English 1
Shepherd (unspecified) 1

Most Reported Reactions

Underfilling, Vials 5
Contamination, Particulate Matter 4
Defect Unknown/Not Specified 4
Missing Cap 3
Panting 2
Bone and joint disorder NOS 2
Abnormal radiograph finding 2
Diarrhoea 1
Comedo/blackhead 1
Lack of efficacy - NOS 1
Swollen joint 1
Skin and tissue infection NOS 1

Outcome Breakdown

Ongoing
6 (75.0%)
Outcome Unknown
1 (12.5%)
Euthanized
1 (12.5%)

Polysulfated Glycosaminoglycan (Psgag): low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Polysulfated Glycosaminoglycan (Psgag) (#1566 of 2,679 by report volume); death-coded 3.8%. PlainBreed drug row · death-coded share stamp 3.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →