Drug profile

The FDA adverse-event record for Polyethylene Glycol 3350

31 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Polyethylene Glycol 3350. See the species affected, top reactions, and outcomes below.

31
adverse-event reports
16.1%
death-coded share
Cat
most-reported species
5
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
31
Total Reports
5
Deaths Reported
16.1%
Death Rate

Active Ingredients

Polyethylene Glycol 3350

Administration Routes

OralUnknown

Species Affected

Cat 30
Human 1

Most Affected Breeds

Domestic Shorthair 19
Domestic Longhair 3
Cat (unknown) 2
Scottish Fold Shorthair 1
American Bobtail 1
Domestic Mediumhair 1
Unknown 1
Tonkinese 1
Russian 1
Siamese 1

Most Reported Reactions

Vomiting 5
Lack of efficacy - NOS 5
Death by euthanasia 3
Vocalisation 3
Diarrhoea 3
Decreased bowel movements 3
Weight loss 3
Not eating 3
Elevated blood urea nitrogen (BUN) 2
Decreased appetite 2
Hypersalivation 2
Death 2

Outcome Breakdown

Recovered/Normal
12 (38.7%)
Ongoing
10 (32.3%)
Outcome Unknown
4 (12.9%)
Euthanized
3 (9.7%)
Died
2 (6.5%)

Polyethylene Glycol 3350 Adverse Event Insights

31 reports name Polyethylene Glycol 3350; 5 recorded a death outcome (16.1% of reported events, not a population-level mortality rate). Active ingredient: Polyethylene Glycol 3350. Administration routes: Oral, Unknown.

By species: Cat (30 reports), Human (1 reports). By breed: Domestic Shorthair (19), Domestic Longhair (3), Cat (unknown) (2).

Leading clinical signs: Vomiting (5), Lack of efficacy - NOS (5), Death by euthanasia (3), Vocalisation (3). Outcome, 31 coded reports: Recovered/Normal leads at 38.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.