Drug profile

The FDA adverse-event record for Phosphate Binder

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Phosphate Binder. See the species affected, top reactions, and outcomes below.

18
adverse-event reports
27.8%
death-coded share
Dog
most-reported species
6
Limb weakness - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
5
Deaths Reported
27.8%
Death Rate

Active Ingredients

Phosphate Binder

Administration Routes

OralUnknown

Species Affected

Dog 10
Cat 8

Most Affected Breeds

Domestic Shorthair 4
Pug 2
Poodle (unspecified) 2
Spaniel - Cocker American 1
Collie - Border 1
Siamese 1
Terrier - Yorkshire 1
Maine Coon 1
Poodle - Standard 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Most Reported Reactions

Limb weakness 6
Death by euthanasia 4
Neuropathy NOS 3
Polyuria 2
Polydipsia 2
Seizure NOS 2
Elevated blood urea nitrogen (BUN) 2
Lack of efficacy - NOS 2
Necropsy performed 2
Lethargy (see also Central nervous system depression in Neurological) 2
Walking difficulty 2
Dilated pupils 2

Outcome Breakdown

Ongoing
8 (44.4%)
Outcome Unknown
4 (22.2%)
Euthanized
4 (22.2%)
Recovered/Normal
1 (5.6%)
Died
1 (5.6%)

Phosphate Binder Adverse Event Insights

18 reports name Phosphate Binder; 5 recorded a death outcome (27.8% of reported events, not a population-level mortality rate). Active ingredient: Phosphate Binder. Administration routes: Oral, Unknown.

By species: Dog (10 reports), Cat (8 reports). By breed: Domestic Shorthair (4), Pug (2), Poodle (unspecified) (2).

Leading clinical signs: Limb weakness (6), Death by euthanasia (4), Neuropathy NOS (3), Polyuria (2). Outcome, 18 coded reports: Ongoing leads at 44.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.