Drug profile

The FDA adverse-event record for Penicillin G Procaine;Novobiocin

21 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Penicillin G Procaine;Novobiocin. See the species affected, top reactions, and outcomes below.

21
adverse-event reports
0.0%
death-coded share
Unknown
most-reported species
6
Difficulty of Use - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
21
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Penicillin G Procaine;Novobiocin

Administration Routes

UnknownIntramammary

Species Affected

Unknown 18
Cattle 3

Most Affected Breeds

Unknown 18
Jersey 1
Cattle (other) 1
Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Difficulty of Use 6
Missing component, medical device 4
Hard, clumping 3
Suspension, Abnormal 3
Underfilling, Container 3
Containers, Damaged 2
Containers, Abnormal 2
Closure, Abnormal 2
Contamination, Foreign Object 2
Syringe, Abnormal 1
Color, Abnormal 1
Drug administration error 1

Outcome Breakdown

Outcome Unknown
3 (75.0%)
Recovered/Normal
1 (25.0%)

Penicillin G Procaine;Novobiocin Adverse Event Insights

21 reports name Penicillin G Procaine;Novobiocin; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Penicillin G Procaine;Novobiocin. Administration routes: Unknown, Intramammary.

By species: Unknown (18 reports), Cattle (3 reports). By breed: Unknown (18), Jersey (1), Cattle (other) (1).

Leading clinical signs: Difficulty of Use (6), Missing component, medical device (4), Hard, clumping (3), Suspension, Abnormal (3). Outcome, 4 coded reports: Outcome Unknown leads at 75.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.