Drug profile

The FDA adverse-event record for Pain Medication

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Pain Medication. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
6.3%
death-coded share
Dog
most-reported species
3
Anorexia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
1
Deaths Reported
6.3%
Death Rate

Active Ingredients

Pain Medication

Administration Routes

UnknownOral

Species Affected

Dog 12
Cat 3
Human 1

Most Affected Breeds

Retriever - Labrador 2
Unknown 1
Maltese 1
Himalayan 1
Greyhound 1
Collie - Border 1
Crossbred Canine/dog 1
Domestic Shorthair 1
Bulldog - French 1
Terrier - Irish Soft-coated Wheaten 1

Most Reported Reactions

Anorexia 3
Vomiting 3
Pain NOS 3
Weight loss 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Twitching 2
Diarrhoea 2
Increased heart rate 2
Wound 2
Taste alteration 1
Behavioural disorder NOS 1
Weight gain 1

Outcome Breakdown

Ongoing
9 (56.3%)
Recovered/Normal
4 (25.0%)
Outcome Unknown
2 (12.5%)
Euthanized
1 (6.3%)

Pain Medication Adverse Event Insights

16 reports name Pain Medication; 1 recorded a death outcome (6.3% of reported events, not a population-level mortality rate). Active ingredient: Pain Medication. Administration routes: Unknown, Oral.

By species: Dog (12 reports), Cat (3 reports), Human (1 reports). By breed: Retriever - Labrador (2), Unknown (1), Maltese (1).

Leading clinical signs: Anorexia (3), Vomiting (3), Pain NOS (3), Weight loss (2). Outcome, 16 coded reports: Ongoing leads at 56.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.