Drug profile

The FDA adverse-event record for Norepinephrine

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Norepinephrine. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
64.0%
death-coded share
Dog
most-reported species
12
Hypotension - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
16
Deaths Reported
64.0%
Death Rate

Active Ingredients

Norepinephrine

Administration Routes

UnknownIntravenousParenteralOther

Species Affected

Dog 18
Cat 6
Human 1

Most Affected Breeds

Retriever - Labrador 4
Domestic Shorthair 4
Retriever - Golden 4
Rottweiler 3
Domestic Longhair 2
Crossbred Canine/dog 2
Unknown 2
Chihuahua 1
Pointing Dog - German Short-haired 1
Terrier - Tibetan 1

Most Reported Reactions

Hypotension 12
Other abnormal test result NOS 11
Dehydration 11
Death by euthanasia 10
Tachycardia 10
Hypoglycaemia 10
Elevated total bilirubin 10
Hypoalbuminaemia 8
Low blood pressure 7
Abdominal effusion 7
Pale mucous membrane 7
Abnormal radiograph finding 7

Outcome Breakdown

Euthanized
10 (40.0%)
Died
6 (24.0%)
Ongoing
5 (20.0%)
Outcome Unknown
2 (8.0%)
Recovered/Normal
2 (8.0%)

Norepinephrine Adverse Event Insights

25 reports name Norepinephrine; 16 recorded a death outcome (64.0% of reported events, not a population-level mortality rate). Active ingredient: Norepinephrine. Administration routes: Unknown, Intravenous, Parenteral, Other.

By species: Dog (18 reports), Cat (6 reports), Human (1 reports). By breed: Retriever - Labrador (4), Domestic Shorthair (4), Retriever - Golden (4).

Leading clinical signs: Hypotension (12), Other abnormal test result NOS (11), Dehydration (11), Death by euthanasia (10). Outcome, 25 coded reports: Euthanized leads at 40.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.