Drug profile

The FDA adverse-event record for Meclizine Hcl

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Meclizine Hcl. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
58.3%
death-coded share
Dog
most-reported species
6
Death by euthanasia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
7
Deaths Reported
58.3%
Death Rate

Active Ingredients

Meclizine Hcl

Administration Routes

OralUnknownOther

Species Affected

Dog 12

Most Affected Breeds

Shepherd Dog - Australian 2
Retriever - Labrador 1
Sheepdog - Old English 1
Bulldog - French 1
Chihuahua 1
Mountain Dog - Bernese 1
Bulldog 1
Pinscher - Miniature 1
Shepherd Dog - German 1
Lhasa Apso 1

Most Reported Reactions

Death by euthanasia 6
Nystagmus 5
Ataxia 4
Vomiting 4
Other abnormal test result NOS 4
Seizure NOS 3
Drooling 3
Head tilt - neurological disorder 3
Decreased appetite 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Trembling 2
Vestibular disorder NOS 2

Outcome Breakdown

Euthanized
6 (50.0%)
Ongoing
3 (25.0%)
Recovered/Normal
2 (16.7%)
Died
1 (8.3%)

Meclizine Hcl Adverse Event Insights

12 reports name Meclizine Hcl; 7 recorded a death outcome (58.3% of reported events, not a population-level mortality rate). Active ingredient: Meclizine Hcl. Administration routes: Oral, Unknown, Other.

By species: Dog (12 reports). By breed: Shepherd Dog - Australian (2), Retriever - Labrador (1), Sheepdog - Old English (1).

Leading clinical signs: Death by euthanasia (6), Nystagmus (5), Ataxia (4), Vomiting (4). Outcome, 12 coded reports: Euthanized leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.