Drug profile

The FDA adverse-event record for Mannheimia Haemolytica Toxoid + Pasteurella Multocida Bacterial Extract

20 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Mannheimia Haemolytica Toxoid + Pasteurella Multocida Bacterial Extract. See the species affected, top reactions, and outcomes below.

20
adverse-event reports
80.0%
death-coded share
Cattle
most-reported species
16
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
20
Total Reports
16
Deaths Reported
80.0%
Death Rate

Active Ingredients

Mannheimia Haemolytica ToxoidPasteurella Multocida Bacterial Extract

Administration Routes

SubcutaneousUnknownIntramuscular

Species Affected

Cattle 20

Most Affected Breeds

Cattle (other) 12
Aberdeen Angus 5
Crossbred Bovine/Cattle 1
Holstein-Friesian also known as Holstein 1
Cattle (unknown) 1

Most Reported Reactions

Death 16
Lack of efficacy - NOS 10
Lack of efficacy (bacteria) - NOS 4
CULTURE/TITER DATA ABNORMAL 2
Respiratory signs 1
INEFFECTIVE, ANTIBIOTIC 1
Tachypnoea 1
Fever 1
Anorexia 1
Lung sound 1
Laboured breathing 1
Abnormal necropsy finding 1

Outcome Breakdown

Died
16 (47.1%)
Recovered/Normal
7 (20.6%)
Ongoing
5 (14.7%)
Outcome Unknown
3 (8.8%)
Recovered with Sequela
3 (8.8%)

Mannheimia Haemolytica Toxoid + Pasteurella Multocida Bacterial Extract Adverse Event Insights

20 reports name Mannheimia Haemolytica Toxoid + Pasteurella Multocida Bacterial Extract; 16 recorded a death outcome (80.0% of reported events, not a population-level mortality rate). Active ingredients: Mannheimia Haemolytica Toxoid, Pasteurella Multocida Bacterial Extract. Administration routes: Subcutaneous, Unknown, Intramuscular.

By species: Cattle (20 reports). By breed: Cattle (other) (12), Aberdeen Angus (5), Crossbred Bovine/Cattle (1).

Leading clinical signs: Death (16), Lack of efficacy - NOS (10), Lack of efficacy (bacteria) - NOS (4), CULTURE/TITER DATA ABNORMAL (2). Outcome, 34 coded reports: Died leads at 47.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.