Mannheimia Haemolytica, Strain Nl-1009

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44 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
44
Total Reports
37
Deaths Reported
8410.0%
Death Rate

Active Ingredients

Mannheimia Haemolytica, Strain Nl-1009

Administration Routes

Subcutaneous

Species Affected

Cattle 44

Most Affected Breeds

Cattle (other) 20
Mixed (Cattle) 16
Holstein-Friesian also known as Holstein 6
Aberdeen Angus 1
Red Angus 1

Most Reported Reactions

Death 28
Lack of efficacy (bacteria) - NOS 18
Lack of efficacy - NOS 16
NT - Abnormal necropsy finding NOS 6
Other abnormal test result NOS 6
Necropsy performed 6
CULTURE/TITER DATA ABNORMAL 5
Lack of efficacy (bacteria) - Mannheimia haemolytica 5
Abnormal test result 4
Increased mortality rate 3
Pulmonary disorder NOS 3
Intentional misuse 3

Outcome Breakdown

Died
37 (51.4%)
Outcome Unknown
21 (29.2%)
Recovered/Normal
7 (9.7%)
Ongoing
4 (5.6%)
Euthanized
3 (4.2%)

Data Summary

Metric Value
Total adverse event reports 44
Reports involving death 37
Case-fatality rate (reported events) 8410.0%
Distinct species in reports 1
Distinct breeds in reports 5
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Mannheimia Haemolytica, Strain Nl-1009 Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 44 adverse event reports referencing Mannheimia Haemolytica, Strain Nl-1009, including 37 reports in which the animal died — a 8410.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Mannheimia Haemolytica, Strain Nl-1009. Reported administration route is Subcutaneous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Mannheimia Haemolytica, Strain Nl-1009 reports are Cattle (44 reports), with Cattle accounting for the largest share. Within those species, Cattle (other) (20), Mixed (Cattle) (16), Holstein-Friesian also known as Holstein (6) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Mannheimia Haemolytica, Strain Nl-1009 are Death (28), Lack of efficacy (bacteria) - NOS (18), Lack of efficacy - NOS (16), NT - Abnormal necropsy finding NOS (6). Of the 72 reports with a coded outcome, Died is the leading category at 51.4%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Mannheimia Haemolytica, Strain Nl-1009.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial