Drug profile

The FDA adverse-event record for Low Fat Diet

36 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Low Fat Diet. Species, reactions, and outcomes follow.

#1324 of 2,679
by report volume (all drugs)
36
adverse-event reports
16.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Low Fat Diet ranks #1311 of 2679 by total reports (36). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1311
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low Fat Diet has 36 reports now versus 36 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low Fat Diet changes

Signature read: Low Fat Diet's 16.7% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
36
Total Reports
6
Deaths Reported
16.7%
Death-coded share of reports

Active Ingredients

Low Fat Diet

Administration Routes

OralUnknown

Species Affected

Dog 36

Most Affected Breeds

Shih Tzu 3
Maltese 3
Crossbred Canine/dog 2
Pinscher - Miniature 2
Schnauzer - Miniature 2
Terrier - Yorkshire 2
Schnauzer (unspecified) 2
Retriever - Golden 2
Beagle 2
Chihuahua 1

Most Reported Reactions

Elevated alanine aminotransferase (ALT) 10
Vomiting 10
Weight loss 8
Diarrhoea 7
Elevated serum alkaline phosphatase (SAP) 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Death by euthanasia 5
High pancreatic-specific lipase 5
Elevated lipase 4
Proteinuria 4
Polydipsia 4
Dental disease 4

Outcome Breakdown

Outcome Unknown
20 (55.6%)
Ongoing
8 (22.2%)
Euthanized
5 (13.9%)
Recovered/Normal
2 (5.6%)
Died
1 (2.8%)

Low Fat Diet Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low Fat Diet (#1324 of 2,679 by report volume); death-coded 16.7%. PlainBreed drug row · death-coded share stamp 16.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →