Drug profile

The FDA adverse-event record for Liver Support Supplement

17 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Liver Support Supplement. See the species affected, top reactions, and outcomes below.

17
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
3
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Liver Support Supplement

Administration Routes

OralUnknownOther

Species Affected

Dog 17

Most Affected Breeds

Chihuahua 3
Shih Tzu 2
Retriever - Labrador 2
Terrier - Cairn 1
Beagle 1
Shepherd Dog - Anatolian 1
Sheepdog - Old English 1
Retriever - Golden 1
Boxer (German Boxer) 1
Crossbred Canine/dog 1

Most Reported Reactions

Lack of efficacy - NOS 3
Vomiting 3
Star-gazing 2
Lack of efficacy (endoparasite) - heartworm 2
Elevated serum alkaline phosphatase (SAP) 2
Elevated alanine aminotransferase (ALT) 2
Diarrhoea 2
Urinary tract infection 2
Tiredness 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Disorientation 1
Lip smacking 1

Outcome Breakdown

Outcome Unknown
8 (47.1%)
Ongoing
6 (35.3%)
Recovered/Normal
3 (17.6%)

Liver Support Supplement Adverse Event Insights

17 reports name Liver Support Supplement; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Liver Support Supplement. Administration routes: Oral, Unknown, Other.

By species: Dog (17 reports). By breed: Chihuahua (3), Shih Tzu (2), Retriever - Labrador (2).

Leading clinical signs: Lack of efficacy - NOS (3), Vomiting (3), Star-gazing (2), Lack of efficacy (endoparasite) - heartworm (2). Outcome, 17 coded reports: Outcome Unknown leads at 47.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.