Drug profile

The FDA adverse-event record for Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
12.5%
death-coded share
Dog
most-reported species
9
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
2
Deaths Reported
12.5%
Death Rate

Active Ingredients

Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate

Administration Routes

Auricular (Otic)

Species Affected

Dog 15
Cat 1

Most Affected Breeds

Spaniel - Cocker American 3
Retriever - Labrador 1
Rottweiler 1
Bichon Frise 1
Bulldog 1
Terrier (unspecified) 1
Shepherd Dog - German 1
Shepherd Dog (unspecified) 1
Pit Bull 1
Retriever - Golden 1

Most Reported Reactions

Lack of efficacy - NOS 9
Loss of hearing 2
CULTURE/TITER DATA ABNORMAL 2
Emesis (multiple) 1
Ear pain 1
Inappropriate urination 1
Polyuria 1
Polydipsia 1
External ear disorder NOS 1
Ear discharge 1
Ulceration NOS 1
Circling - neurological disorder (see also 'Behavioural disorders') 1

Outcome Breakdown

Outcome Unknown
8 (50.0%)
Recovered/Normal
5 (31.3%)
Ongoing
1 (6.3%)
Euthanized
1 (6.3%)
Died
1 (6.3%)

Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate Adverse Event Insights

16 reports name Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate; 2 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). Active ingredient: Lactic Acid + Salicylic Acid + Benzoic Acid + Dioctyl Sodium Sulfoscuccinate. Administration route: Auricular (Otic).

By species: Dog (15 reports), Cat (1 reports). By breed: Spaniel - Cocker American (3), Retriever - Labrador (1), Rottweiler (1).

Leading clinical signs: Lack of efficacy - NOS (9), Loss of hearing (2), CULTURE/TITER DATA ABNORMAL (2), Emesis (multiple) (1). Outcome, 16 coded reports: Outcome Unknown leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.