Lactated Ringer&Apos;S Solution

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34 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
34
Total Reports
10
Deaths Reported
2940.0%
Death Rate

Active Ingredients

Lactated Ringer&Apos;S Solution

Administration Routes

IntravenousSubcutaneousUnknownIntra-ArticularOther

Species Affected

Dog 20
Cat 9
Horse 3
Other Birds 1
Guinea Pig 1

Most Affected Breeds

Domestic Shorthair 5
Pit Bull 3
Retriever - Golden 2
Unknown 2
Crossbred Canine/dog 2
Boxer (German Boxer) 2
Schipperke 2
Trakehner 2
Rex - Devon 1
Mixed (Dog) 1

Most Reported Reactions

Vomiting 8
Death 5
Hypersalivation 5
Death by euthanasia 5
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Other abnormal test result NOS 4
Lethargy (see also Central nervous system depression in Neurological) 4
Lack of efficacy - NOS 4
Tachycardia 4
Vocalisation 3
Ataxia 3

Outcome Breakdown

Recovered/Normal
12 (35.3%)
Outcome Unknown
7 (20.6%)
Died
5 (14.7%)
Euthanized
5 (14.7%)
Ongoing
5 (14.7%)

Data Summary

Metric Value
Total adverse event reports 34
Reports involving death 10
Case-fatality rate (reported events) 2940.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Lactated Ringer&Apos;S Solution Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 34 adverse event reports referencing Lactated Ringer&Apos;S Solution, including 10 reports in which the animal died — a 2940.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Lactated Ringer&Apos;S Solution. Reported administration routes include Intravenous, Subcutaneous, Unknown, Intra-Articular. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Lactated Ringer&Apos;S Solution reports are Dog (20 reports), Cat (9 reports), Horse (3 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (5), Pit Bull (3), Retriever - Golden (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Lactated Ringer&Apos;S Solution are Vomiting (8), Death (5), Hypersalivation (5), Death by euthanasia (5). Of the 34 reports with a coded outcome, Recovered/Normal is the leading category at 35.3%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Lactated Ringer&Apos;S Solution.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial