Drug profile

The FDA adverse-event record for Ketoconazole, Trizedta

Name: Ketoconazole, Trizedta - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

11 FDA reports name Ketoconazole, Trizedta, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2472 of 2,679
by report volume (all drugs): 11
adverse-event reports: 0.0%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ketoconazole, Trizedta ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: 11 reports place Ketoconazole, Trizedta in the lower third of FDA AER volume (#2472 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death-coded share of reports

Active Ingredients

Ketoconazole, Trizedta

Administration Routes

Auricular (Otic)UnknownTopical

Species Affected

Dog 8

Cat 3

Most Affected Breeds

Spaniel - Springer (unspecified) 2

Domestic Shorthair 2

Chow Chow 2

Retriever - Golden 1

Catahoula Leopard Dog 1

Terrier - Bull - Staffordshire 1

Cat (unknown) 1

Spaniel - King Charles Cavalier 1

Most Reported Reactions

Lack of efficacy - NOS 3

Limb weakness 3

Ataxia 3

Weight loss 3

Decreased appetite 3

Loss of hearing 2

Head bobbing 2

Otitis externa 2

Epiphora 2

Reluctant to move 2

Ear irritation 2

Medication error NOS 2

Outcome Breakdown

Ongoing

7 (63.6%)

Recovered/Normal

2 (18.2%)

Recovered with Sequela

1 (9.1%)

Outcome Unknown

1 (9.1%)

Ketoconazole, Trizedta: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ketoconazole, Trizedta (#2472 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →