Drug profile

The FDA adverse-event record for Kennel Cough Vaccine

39 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Kennel Cough Vaccine. Species, reactions, and outcomes follow.

#1270 of 2,679
by report volume (all drugs)
39
adverse-event reports
10.3%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Kennel Cough Vaccine ranks #1263 of 2679 by total reports (39). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1263
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Kennel Cough Vaccine has 39 reports now versus 38 in that prior snapshot: 1 more (2.6%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Kennel Cough Vaccine changes

Signature read: report volume at 39 is the most distinctive stamp on Kennel Cough Vaccine's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
39
Total Reports
4
Deaths Reported
10.3%
Death-coded share of reports

Active Ingredients

Kennel Cough Vaccine

Administration Routes

UnknownNasalOralParenteralSubcutaneous

Species Affected

Dog 39

Most Affected Breeds

Retriever - Labrador 8
Terrier - Yorkshire 2
Terrier (unspecified) 2
Chihuahua 2
Retriever - Golden 2
Crossbred Canine/dog 2
Brittany 2
Terrier - Jack Russell 2
Bichon Frise 2
Shih Tzu 1

Most Reported Reactions

Vomiting 11
Lack of efficacy (endoparasite) - heartworm 7
Other abnormal test result NOS 5
Behavioural disorder NOS 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Seizure NOS 4
Diarrhoea 4
Abnormal radiograph finding 4
Itching 4
Loss of hearing 3
Injection site reaction NOS 3
Weight gain 2

Outcome Breakdown

Recovered/Normal
14 (35.9%)
Outcome Unknown
12 (30.8%)
Ongoing
8 (20.5%)
Euthanized
2 (5.1%)
Died
2 (5.1%)
Recovered with Sequela
1 (2.6%)

Kennel Cough Vaccine Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Kennel Cough Vaccine (#1270 of 2,679 by report volume); death-coded 10.3%. PlainBreed drug row · report volume stamp 39 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →