Drug profile

The FDA adverse-event record for Ivermectin 1.87% Parziquantel 14.03%

33 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin 1.87% Parziquantel 14.03%. Species, reactions, and outcomes follow.

#1377 of 2,679
by report volume (all drugs)
33
adverse-event reports
15.2%
death-coded share
Horse
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ivermectin 1.87% Parziquantel 14.03% ranks #1367 of 2679 by total reports (33). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1367
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ivermectin 1.87% Parziquantel 14.03% has 33 reports now versus 33 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ivermectin 1.87% Parziquantel 14.03% changes

Signature read: death-coded share at 15.2% is the most distinctive stamp on Ivermectin 1.87% Parziquantel 14.03%'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
33
Total Reports
5
Deaths Reported
15.2%
Death-coded share of reports

Active Ingredients

Ivermectin 1.87% Parziquantel 14.03%

Administration Routes

OralUnknown

Species Affected

Horse 16
Unknown 12
Dog 3
Cat 2

Most Affected Breeds

Unknown 13
Quarter Horse 5
Horse (unknown) 3
Collie (unspecified) 2
Warmblood - Dutch 1
Domestic Shorthair 1
Domestic Mediumhair 1
Shih Tzu 1
Paint 1
Horse (other) 1

Most Reported Reactions

Uncoded sign 6
Ataxia 5
Underfilling, Tubes 5
Colic 4
Death 3
Death by euthanasia 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Diarrhoea 3
Locking Mechanism Abnormal 3
Product problem 3
Underfilling, Container 3
Depression 2

Outcome Breakdown

Outcome Unknown
9 (40.9%)
Recovered/Normal
7 (31.8%)
Died
3 (13.6%)
Euthanized
3 (13.6%)

Ivermectin 1.87% Parziquantel 14.03% Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ivermectin 1.87% Parziquantel 14.03% (#1377 of 2,679 by report volume); death-coded 15.2%. PlainBreed drug row · death-coded share stamp 15.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →