Drug profile

The FDA adverse-event record for Isoflurane Gas

23 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Isoflurane Gas. See the species affected, top reactions, and outcomes below.

23
adverse-event reports
39.1%
death-coded share
Dog
most-reported species
8
Vocalisation - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
23
Total Reports
9
Deaths Reported
39.1%
Death Rate

Active Ingredients

Isoflurane Gas

Administration Routes

Respiratory (Inhalation)UnknownOtherNasal

Species Affected

Dog 15
Cat 7
Rabbit 1

Most Affected Breeds

Retriever - Labrador 3
Domestic Shorthair 3
Siberian Husky 3
Maltese 2
Dog (other) 2
Domestic Mediumhair 2
Retriever - Golden 1
Bulldog 1
Poodle (unspecified) 1
Chihuahua 1

Most Reported Reactions

Vocalisation 8
Not eating 7
Death by euthanasia 6
Elevated creatinine 6
Abnormal ultrasound finding 6
Panting 5
Ataxia 5
Digestive tract disorder NOS 5
Anxiety 5
Temporary blindness 4
Bumping into walls 4
Sedation prolonged 4

Outcome Breakdown

Recovered/Normal
7 (30.4%)
Euthanized
6 (26.1%)
Outcome Unknown
6 (26.1%)
Died
3 (13.0%)
Ongoing
1 (4.3%)

Isoflurane Gas Adverse Event Insights

23 reports name Isoflurane Gas; 9 recorded a death outcome (39.1% of reported events, not a population-level mortality rate). Active ingredient: Isoflurane Gas. Administration routes: Respiratory (Inhalation), Unknown, Other, Nasal.

By species: Dog (15 reports), Cat (7 reports), Rabbit (1 reports). By breed: Retriever - Labrador (3), Domestic Shorthair (3), Siberian Husky (3).

Leading clinical signs: Vocalisation (8), Not eating (7), Death by euthanasia (6), Elevated creatinine (6). Outcome, 23 coded reports: Recovered/Normal leads at 30.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.