Drug profile

The FDA adverse-event record for Isofluorane

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Isofluorane. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
16.0%
death-coded share
Dog
most-reported species
8
Apnoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
4
Deaths Reported
16.0%
Death Rate

Active Ingredients

Isofluorane

Administration Routes

Respiratory (Inhalation)UnknownOther

Species Affected

Dog 17
Cat 7
Rabbit 1

Most Affected Breeds

Domestic Shorthair 3
Cat (unknown) 3
Retriever - Labrador 3
Shih Tzu 2
Lop - French 1
Mixed (Dog) 1
Terrier - Airedale 1
Crossbred Canine/dog 1
Coonhound (unspecified) 1
Dachshund - Standard Smooth-haired 1

Most Reported Reactions

Apnoea 8
Lethargy (see also Central nervous system depression in 'Neurological') 5
Death 4
Ataxia 3
Vomiting 3
Leucocytosis NOS 3
Diarrhoea 2
Pruritus 2
Other abnormal test result NOS 2
Fever 2
Anorexia 2
Hyperphosphataemia 2

Outcome Breakdown

Recovered/Normal
16 (64.0%)
Died
4 (16.0%)
Outcome Unknown
3 (12.0%)
Ongoing
2 (8.0%)

Isofluorane Adverse Event Insights

25 reports name Isofluorane; 4 recorded a death outcome (16.0% of reported events, not a population-level mortality rate). Active ingredient: Isofluorane. Administration routes: Respiratory (Inhalation), Unknown, Other.

By species: Dog (17 reports), Cat (7 reports), Rabbit (1 reports). By breed: Domestic Shorthair (3), Cat (unknown) (3), Retriever - Labrador (3).

Leading clinical signs: Apnoea (8), Lethargy (see also Central nervous system depression in 'Neurological') (5), Death (4), Ataxia (3). Outcome, 25 coded reports: Recovered/Normal leads at 64.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.