Drug profile

The FDA adverse-event record for Ibr, Pi3, Brsv

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ibr, Pi3, Brsv. See the species affected, top reactions, and outcomes below.

14
adverse-event reports
92.9%
death-coded share
Cattle
most-reported species
11
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
13
Deaths Reported
92.9%
Death Rate

Active Ingredients

Ibr, Pi3, Brsv

Administration Routes

UnknownNasal

Species Affected

Cattle 14

Most Affected Breeds

Cattle (other) 7
Holstein-Friesian also known as Holstein 3
Crossbred Bovine/Cattle 3
Hereford cattle 1

Most Reported Reactions

Death 11
Lack of efficacy - NOS 8
INEFFECTIVE, ANTIBIOTIC 4
Lack of efficacy (bacteria) - NOS 2
Found dead 2
Respiratory signs 1
Abnormal test result 1
Bloated 1
Septicaemia 1
CULTURE/TITER DATA ABNORMAL 1
Anaphylaxis 1

Outcome Breakdown

Died
13 (50.0%)
Ongoing
7 (26.9%)
Recovered/Normal
5 (19.2%)
Outcome Unknown
1 (3.8%)

Ibr, Pi3, Brsv Adverse Event Insights

14 reports name Ibr, Pi3, Brsv; 13 recorded a death outcome (92.9% of reported events, not a population-level mortality rate). Active ingredient: Ibr, Pi3, Brsv. Administration routes: Unknown, Nasal.

By species: Cattle (14 reports). By breed: Cattle (other) (7), Holstein-Friesian also known as Holstein (3), Crossbred Bovine/Cattle (3).

Leading clinical signs: Death (11), Lack of efficacy - NOS (8), INEFFECTIVE, ANTIBIOTIC (4), Lack of efficacy (bacteria) - NOS (2). Outcome, 26 coded reports: Died leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.