Drug profile

The FDA adverse-event record for Hygromycin B

29 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hygromycin B. See the species affected, top reactions, and outcomes below.

29
adverse-event reports
24.1%
death-coded share
Chicken
most-reported species
10
INEFFECTIVE, WORMS NOS - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
29
Total Reports
7
Deaths Reported
24.1%
Death Rate

Active Ingredients

Hygromycin B

Administration Routes

OralUnknownTopical

Species Affected

Chicken 26
Unknown 2
Human 1

Most Affected Breeds

Chicken (unknown) 20
Chicken (other) 5
Unknown 3
Chicken (unspecified) 1

Most Reported Reactions

INEFFECTIVE, WORMS NOS 10
Death 7
INEFFECTIVE, ASCARIDS NOS 7
Lack of efficacy (endoparasite) - roundworm NOS 6
Lack of efficacy - NOS 4
Liver disorder NOS 3
Uncoded sign 2
NT - Abnormal necropsy finding NOS 2
Pericarditis 1
Hepatic fibrosis 1
PR-CECUM, LESION(S) 1
Reduced hatchability 1

Outcome Breakdown

Outcome Unknown
19 (65.5%)
Died
7 (24.1%)
Recovered/Normal
2 (6.9%)
Recovered with Sequela
1 (3.4%)

Hygromycin B Adverse Event Insights

29 reports name Hygromycin B; 7 recorded a death outcome (24.1% of reported events, not a population-level mortality rate). Active ingredient: Hygromycin B. Administration routes: Oral, Unknown, Topical.

By species: Chicken (26 reports), Unknown (2 reports), Human (1 reports). By breed: Chicken (unknown) (20), Chicken (other) (5), Unknown (3).

Leading clinical signs: INEFFECTIVE, WORMS NOS (10), Death (7), INEFFECTIVE, ASCARIDS NOS (7), Lack of efficacy (endoparasite) - roundworm NOS (6). Outcome, 29 coded reports: Outcome Unknown leads at 65.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.