Drug profile

The FDA adverse-event record for Hetacillin Potassium

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hetacillin Potassium. See the species affected, top reactions, and outcomes below.

18
adverse-event reports
5.6%
death-coded share
Cattle
most-reported species
5
Residues in milk - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
1
Deaths Reported
5.6%
Death Rate

Active Ingredients

Hetacillin Potassium

Administration Routes

UnknownIntramammary

Species Affected

Cattle 11
Unknown 7

Most Affected Breeds

Holstein-Friesian also known as Holstein 8
Unknown 7
Jersey 1
Cattle (other) 1
Cattle (unknown) 1

Most Reported Reactions

Residues in milk 5
Lack of efficacy (bacteria) - NOS 5
Product Defect, General 2
Containers, Damaged 2
Caps, Abnormal 1
Product syringe issue 1
Underfilling, Package 1
Tubes, Damaged 1
INEFFECTIVE, ANTIBIOTIC 1
Mammary gland disorder NOS 1
Alteration of milk quality 1
Death 1

Outcome Breakdown

Outcome Unknown
7 (58.3%)
Recovered/Normal
4 (33.3%)
Died
1 (8.3%)

Hetacillin Potassium Adverse Event Insights

18 reports name Hetacillin Potassium; 1 recorded a death outcome (5.6% of reported events, not a population-level mortality rate). Active ingredient: Hetacillin Potassium. Administration routes: Unknown, Intramammary.

By species: Cattle (11 reports), Unknown (7 reports). By breed: Holstein-Friesian also known as Holstein (8), Unknown (7), Jersey (1).

Leading clinical signs: Residues in milk (5), Lack of efficacy (bacteria) - NOS (5), Product Defect, General (2), Containers, Damaged (2). Outcome, 12 coded reports: Outcome Unknown leads at 58.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.