Drug profile

The FDA adverse-event record for Glycopyrolate

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glycopyrolate. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
18.2%
death-coded share
Dog
most-reported species
4
Pale mucous membrane - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
2
Deaths Reported
18.2%
Death Rate

Active Ingredients

Glycopyrolate

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 10
Cat 1

Most Affected Breeds

Spaniel (unspecified) 2
Coonhound - Black and Tan 1
Domestic Shorthair 1
Crossbred Canine/dog 1
Doberman Pinscher 1
Terrier - Boston 1
Corgi - Welsh Cardigan 1
Collie (unspecified) 1
Dog (unknown) 1
Retriever - Golden 1

Most Reported Reactions

Pale mucous membrane 4
Respiratory arrest 3
Collapse NOS (see also Cardio-vascular and Neurological disorders) 3
Immune mediated haemolytic anaemia 3
Immune mediated thrombocytopenia 3
Ascites 2
Other abnormal test result NOS 2
Abnormal radiograph finding 2
Malaise 2
Elevated creatinine 2
Hypothermia 2
Vomiting 2

Outcome Breakdown

Recovered/Normal
4 (36.4%)
Ongoing
4 (36.4%)
Recovered with Sequela
1 (9.1%)
Euthanized
1 (9.1%)
Died
1 (9.1%)

Glycopyrolate Adverse Event Insights

11 reports name Glycopyrolate; 2 recorded a death outcome (18.2% of reported events, not a population-level mortality rate). Active ingredient: Glycopyrolate. Administration routes: Unknown, Subcutaneous.

By species: Dog (10 reports), Cat (1 reports). By breed: Spaniel (unspecified) (2), Coonhound - Black and Tan (1), Domestic Shorthair (1).

Leading clinical signs: Pale mucous membrane (4), Respiratory arrest (3), Collapse NOS (see also Cardio-vascular and Neurological disorders) (3), Immune mediated haemolytic anaemia (3). Outcome, 11 coded reports: Recovered/Normal leads at 36.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.