Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables

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47 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
47
Total Reports
7
Deaths Reported
1490.0%
Death Rate

Active Ingredients

Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables

Administration Routes

Oral

Species Affected

Dog 45
Cat 2

Most Affected Breeds

Retriever - Labrador 10
Shepherd Dog - German 5
Rottweiler 3
Crossbred Canine/dog 2
Pug 2
Collie - Border 2
Doberman Pinscher 1
Mixed (Dog) 1
Domestic Mediumhair 1
Collie - Rough-haired 1

Most Reported Reactions

Other abnormal test result NOS 17
Lethargy (see also Central nervous system depression in 'Neurological') 12
Emesis 8
Vomiting 7
Death by euthanasia 6
Anorexia 6
Weight loss 6
Diarrhoea 6
Weakness 4
Anxiety 4
Elevated serum alkaline phosphatase (SAP) 4
Elevated alanine aminotransferase (ALT) 4

Outcome Breakdown

Recovered/Normal
17 (36.2%)
Ongoing
13 (27.7%)
Outcome Unknown
10 (21.3%)
Euthanized
6 (12.8%)
Died
1 (2.1%)

Data Summary

Metric Value
Total adverse event reports 47
Reports involving death 7
Case-fatality rate (reported events) 1490.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 47 adverse event reports referencing Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables, including 7 reports in which the animal died — a 1490.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables. Reported administration route is Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables reports are Dog (45 reports), Cat (2 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (10), Shepherd Dog - German (5), Rottweiler (3) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables are Other abnormal test result NOS (17), Lethargy (see also Central nervous system depression in 'Neurological') (12), Emesis (8), Vomiting (7). Of the 47 reports with a coded outcome, Recovered/Normal is the leading category at 36.2%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Glucosamine/Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial