Drug profile

The FDA adverse-event record for Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
33.3%
death-coded share
Dog
most-reported species
9
Other abnormal test result NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
5
Deaths Reported
33.3%
Death Rate

Active Ingredients

Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables

Administration Routes

Oral

Species Affected

Dog 15

Most Affected Breeds

Retriever - Labrador 6
Doberman Pinscher 2
Retriever - Golden 2
Mixed (Dog) 1
Mastiff 1
Terrier - Jack Russell 1
Beagle 1
Spaniel - Cocker American 1

Most Reported Reactions

Other abnormal test result NOS 9
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Intestinal perforation 4
Tachypnoea 3
Abdominal discomfort 3
Vomiting 2
Death 2
Tachycardia 2
Peritonitis 2
Emesis 2
Death by euthanasia 2

Outcome Breakdown

Euthanized
4 (26.7%)
Recovered/Normal
4 (26.7%)
Outcome Unknown
3 (20.0%)
Ongoing
2 (13.3%)
Died
1 (6.7%)
Recovered with Sequela
1 (6.7%)

Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables Adverse Event Insights

15 reports name Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables; 5 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). Active ingredient: Glucosamine/ Chondroitin Sulfate Plus Avocado/Soybean Unsaponifiables. Administration route: Oral.

By species: Dog (15 reports). By breed: Retriever - Labrador (6), Doberman Pinscher (2), Retriever - Golden (2).

Leading clinical signs: Other abnormal test result NOS (9), Diarrhoea (4), Lethargy (see also Central nervous system depression in 'Neurological') (4), Intestinal perforation (4). Outcome, 15 coded reports: Euthanized leads at 26.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.