Drug profile

The FDA adverse-event record for Fluticasone Propionate

44 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fluticasone Propionate. See the species affected, top reactions, and outcomes below.

44
adverse-event reports
6.8%
death-coded share
Cat
most-reported species
8
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
44
Total Reports
3
Deaths Reported
6.8%
Death Rate

Active Ingredients

Fluticasone Propionate

Administration Routes

UnknownRespiratory (Inhalation)NasalOther

Species Affected

Cat 22
Dog 15
Human 5
Unknown 2

Most Affected Breeds

Domestic Shorthair 14
Unknown 7
Maltese 3
Crossbred Canine/dog 2
Cat (unknown) 2
Maine Coon 2
American Shorthair 1
Boxer (German Boxer) 1
Dachshund (unspecified) 1
Rex - Devon 1

Most Reported Reactions

Vomiting 8
Other abnormal test result NOS 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Decreased appetite 3
Emesis 3
Asthma 3
Cough 3
Not eating 3
Abnormal radiograph finding 3
Death by euthanasia 3
Diarrhoea 3
Hypersalivation 3

Outcome Breakdown

Ongoing
18 (42.9%)
Outcome Unknown
13 (31.0%)
Recovered/Normal
8 (19.0%)
Euthanized
3 (7.1%)

Fluticasone Propionate Adverse Event Insights

44 reports name Fluticasone Propionate; 3 recorded a death outcome (6.8% of reported events, not a population-level mortality rate). Active ingredient: Fluticasone Propionate. Administration routes: Unknown, Respiratory (Inhalation), Nasal, Other.

By species: Cat (22 reports), Dog (15 reports), Human (5 reports). By breed: Domestic Shorthair (14), Unknown (7), Maltese (3).

Leading clinical signs: Vomiting (8), Other abnormal test result NOS (6), Lethargy (see also Central nervous system depression in 'Neurological') (5), Decreased appetite (3). Outcome, 42 coded reports: Ongoing leads at 42.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.