Drug profile

The FDA adverse-event record for Fluticasone Propionate

48 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fluticasone Propionate. Species, reactions, and outcomes follow.

#1147 of 2,679
by report volume (all drugs)
48
adverse-event reports
6.3%
death-coded share
Cat
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Fluticasone Propionate ranks #1140 of 2679 by total reports (48). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1140
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fluticasone Propionate has 48 reports now versus 44 in that prior snapshot: 4 more (9.1%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fluticasone Propionate changes

Signature read: death-coded share at 6.3% is the most distinctive stamp on Fluticasone Propionate's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
3
Deaths Reported
6.3%
Death-coded share of reports

Active Ingredients

Fluticasone Propionate

Administration Routes

UnknownRespiratory (Inhalation)NasalOther

Species Affected

Cat 26
Dog 15
Human 5
Unknown 2

Most Affected Breeds

Domestic Shorthair 15
Unknown 7
Maltese 3
Crossbred Canine/dog 2
Cat (unknown) 2
Domestic Mediumhair 2
Maine Coon 2
Russian 2
American Shorthair 1
Boxer (German Boxer) 1

Most Reported Reactions

Vomiting 11
Other abnormal test result NOS 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Lethargy (see also Central nervous system depression in Neurological) 5
Decreased appetite 4
Diarrhoea 4
Drooling 3
Emesis 3
Asthma 3
Cough 3
Not eating 3
Abnormal radiograph finding 3

Outcome Breakdown

Ongoing
20 (43.5%)
Outcome Unknown
15 (32.6%)
Recovered/Normal
8 (17.4%)
Euthanized
3 (6.5%)

Fluticasone Propionate Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fluticasone Propionate (#1147 of 2,679 by report volume); death-coded 6.3%. PlainBreed drug row · death-coded share stamp 6.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →