Drug profile

The FDA adverse-event record for Flea & Tick Collar For Dogs

42 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flea & Tick Collar For Dogs. See the species affected, top reactions, and outcomes below.

42
adverse-event reports
7.1%
death-coded share
Dog
most-reported species
8
Lack of efficacy (ectoparasite) - tick NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
42
Total Reports
3
Deaths Reported
7.1%
Death Rate

Active Ingredients

Flea & Tick Collar For Dogs

Administration Routes

TopicalUnknown

Species Affected

Dog 42

Most Affected Breeds

Shih Tzu 5
Chihuahua 4
Terrier - Yorkshire 4
Retriever - Labrador 3
Terrier - Cairn 3
Maltese 3
Terrier (unspecified) 2
Schnauzer - Miniature 2
Beagle 2
Retriever - Golden 2

Most Reported Reactions

Lack of efficacy (ectoparasite) - tick NOS 8
Pruritus 7
Lethargy (see also Central nervous system depression in 'Neurological') 6
Restlessness 5
Elevated alanine aminotransferase (ALT) 4
Elevated serum alkaline phosphatase (SAP) 4
Pain NOS 4
Lack of efficacy (ectoparasite) - flea 4
Diarrhoea 3
Vomiting 3
Lack of efficacy - NOS 3
Elevated liver enzymes 3

Outcome Breakdown

Ongoing
18 (42.9%)
Recovered/Normal
12 (28.6%)
Outcome Unknown
9 (21.4%)
Died
2 (4.8%)
Euthanized
1 (2.4%)

Flea & Tick Collar For Dogs Adverse Event Insights

42 reports name Flea & Tick Collar For Dogs; 3 recorded a death outcome (7.1% of reported events, not a population-level mortality rate). Active ingredient: Flea & Tick Collar For Dogs. Administration routes: Topical, Unknown.

By species: Dog (42 reports). By breed: Shih Tzu (5), Chihuahua (4), Terrier - Yorkshire (4).

Leading clinical signs: Lack of efficacy (ectoparasite) - tick NOS (8), Pruritus (7), Lethargy (see also Central nervous system depression in 'Neurological') (6), Restlessness (5). Outcome, 42 coded reports: Ongoing leads at 42.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.