Fipronil/Methoprene

16 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

1250.0%

Death Rate

Active Ingredients

Fipronil/Methoprene

Administration Routes

TopicalUnknown

Species Affected

Cat 8

Dog 8

Most Affected Breeds

Domestic Shorthair 8

Terrier - Yorkshire 2

Spitz - American Eskimo Dog 1

Collie (unspecified) 1

Shepherd Dog - German 1

Mixed (Dog) 1

Shepherd Dog - Belgian Laekenois 1

Terrier - Border 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 4

Stiffness limb 3

Hyperactivity 2

Vocalisation 2

Scratching 2

Seizure NOS 2

Cardiac enlargement 2

Limb weakness 2

Paraparesis 2

Pulmonary disorder NOS 2

Urinary retention 2

Lateral recumbency 2

Outcome Breakdown

Recovered/Normal

7 (43.8%)

Ongoing

5 (31.3%)

Outcome Unknown

2 (12.5%)

Euthanized

2 (12.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.