Fipronil + (S)-Methoprene + Pyriproxyfen
40 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
40
Total Reports
0
Deaths Reported
0.0%
Death Rate
Active Ingredients
Fipronil + (S)-Methoprene + Pyriproxyfen
Administration Routes
TopicalUnknownOther
Species Affected
Dog 33
Cat 7
Most Affected Breeds
Crossbred Canine/dog 5
Domestic Shorthair 3
Retriever - Labrador 3
Shepherd Dog - German 3
Terrier - Yorkshire 3
Domestic Longhair 2
Shepherd Dog - Australian 2
Retriever - Golden 2
Persian 2
Beagle 2
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 8
Other abnormal test result NOS 8
Vomiting 7
Lethargy (see also Central nervous system depression in 'Neurological') 6
Enlarged liver 4
Elevated serum alkaline phosphatase (SAP) 3
Licking 3
Agitation 3
INEFFECTIVE, HOOKS 3
Shaking 3
Weakness 3
Lack of efficacy (ectoparasite) - flea 2
Outcome Breakdown
Outcome Unknown
22 (55.0%)
Recovered/Normal
9 (22.5%)
Ongoing
9 (22.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.