Fipronil 10%/S Methoprene 12% Spot On

47 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

430.0%

Death Rate

Active Ingredients

Fipronil 10%/S Methoprene 12% Spot On

Administration Routes

TopicalUnknownOther

Species Affected

Cat 43

Dog 4

Most Affected Breeds

Domestic Shorthair 24

Domestic Mediumhair 6

Cat (unknown) 5

Mixed (Cat) 2

Unknown 1

Himalayan 1

Retriever - Labrador 1

Spaniel - King Charles Cavalier 1

Crossbred Canine/dog 1

Havanese 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 14

Application site hair loss 7

Lethargy (see also Central nervous system depression in 'Neurological') 6

Vomiting 6

Application site irritation 4

Hair loss NOS 4

Behavioural disorder NOS 3

Scratching 3

Reddening of the skin 3

Skin sore 2

Application site ulcer 2

Application site hair change 2

Outcome Breakdown

Outcome Unknown

30 (63.8%)

Recovered/Normal

8 (17.0%)

Ongoing

7 (14.9%)

Euthanized

1 (2.1%)

Died

1 (2.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.