Drug profile

The FDA adverse-event record for Fentanyl Patch

13 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fentanyl Patch. See the species affected, top reactions, and outcomes below.

13
adverse-event reports
53.8%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13
Total Reports
7
Deaths Reported
53.8%
Death Rate

Active Ingredients

Fentanyl Patch

Administration Routes

TopicalTransdermalUnknown

Species Affected

Dog 9
Cat 4

Most Affected Breeds

Domestic Shorthair 3
Chihuahua 2
Terrier - Irish Soft-coated Wheaten 2
Havanese 2
Retriever - Golden 1
Siberian Husky 1
Dog (other) 1
Siamese 1

Most Reported Reactions

Vomiting 5
Anorexia 5
Death by euthanasia 5
Not eating 4
Other abnormal test result NOS 3
Elevated creatinine 3
Dehydration 2
Hyperphosphataemia 2
Pale mucous membrane 2
Tachypnoea 2
Limb weakness 2
High pancreatic-specific lipase 2

Outcome Breakdown

Euthanized
5 (38.5%)
Recovered/Normal
3 (23.1%)
Died
2 (15.4%)
Outcome Unknown
1 (7.7%)
Recovered with Sequela
1 (7.7%)
Ongoing
1 (7.7%)

Fentanyl Patch Adverse Event Insights

13 reports name Fentanyl Patch; 7 recorded a death outcome (53.8% of reported events, not a population-level mortality rate). Active ingredient: Fentanyl Patch. Administration routes: Topical, Transdermal, Unknown.

By species: Dog (9 reports), Cat (4 reports). By breed: Domestic Shorthair (3), Chihuahua (2), Terrier - Irish Soft-coated Wheaten (2).

Leading clinical signs: Vomiting (5), Anorexia (5), Death by euthanasia (5), Not eating (4). Outcome, 13 coded reports: Euthanized leads at 38.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.