Drug profile

The FDA adverse-event record for Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain

29 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain. Species, reactions, and outcomes follow.

#1473 of 2,679
by report volume (all drugs)
29
adverse-event reports
6.9%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain ranks #1463 of 2679 by total reports (29). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1463
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain has 29 reports now versus 25 in that prior snapshot: 4 more (16.0%).

Report change
+4
Death-coded reports
+0
Death-coded share
−1.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain changes

Signature read: death-coded report count at 2 is the most distinctive stamp on Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
29
Total Reports
2
Deaths Reported
6.9%
Death-coded share of reports

Active Ingredients

Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain

Administration Routes

SubcutaneousUnknown

Species Affected

Cat 29

Most Affected Breeds

Domestic Shorthair 16
Domestic Mediumhair 5
Siamese 2
Domestic Longhair 2
Bengal 1
Cat (unknown) 1
Ragdoll 1
Persian 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 19
Not eating 11
Fever 11
Anorexia 7
Not drinking 6
Vomiting 5
Injection site pain 5
Emesis (multiple) 5
Dehydration 5
Other abnormal test result NOS 5
Distress 4
Adipsia 3

Outcome Breakdown

Recovered/Normal
16 (55.2%)
Outcome Unknown
6 (20.7%)
Ongoing
5 (17.2%)
Died
2 (6.9%)

Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain (#1473 of 2,679 by report volume); death-coded 6.9%. PlainBreed drug row · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →