Drug profile

Here's what the FDA CVM extract says about Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain

Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain carries 11 FDA reports, lower-volume in the CVM extract. Read on for species, reactions, and outcomes.

#2448 of 2,679
by report volume (all drugs)
11
adverse-event reports
36.4%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: 11 reports place Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain in the lower third of FDA AER volume (#2448 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
4
Deaths Reported
36.4%
Death-coded share of reports

Active Ingredients

Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain

Administration Routes

Subcutaneous

Species Affected

Cat 11

Most Affected Breeds

Domestic Shorthair 5
Domestic Longhair 3
Ragdoll 1
Domestic Mediumhair 1
Siamese 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 9
Diarrhoea 4
Death by euthanasia 4
Not eating 3
Fever 3
Vomiting 3
Anaemia NOS 3
Other abnormal test result NOS 3
Behavioural disorder NOS 2
Not drinking 2
Discomfort NOS 2
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 2

Outcome Breakdown

Euthanized
4 (36.4%)
Recovered/Normal
4 (36.4%)
Ongoing
3 (27.3%)

Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Next steps with this data

  • Before drawing conclusions from this number, read why death-coded share is not the same thing as a mortality rate. Understanding adverse events
  • See how this report count compares across the full drug directory. All drugs

Correlation in adverse-event counts is not causation; consult a veterinarian before making a decision from this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Feline Calicivirus, 255 Strain,Feline Calicivirus, Dd1 Strain,Feline Leukemia Virus, Ah927/1161E Strain,Feline Panleukopenia Virus, Cu-4 Strain,Feline Viral Rhinotracheitis, 605 Strain (#2448 of 2,679 by report volume); death-coded 36.4%. PlainBreed drug row · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →