Drug profile

The FDA adverse-event record for Extended Release Trenbolone Acetate And Estradiol Implant

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Extended Release Trenbolone Acetate And Estradiol Implant. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
75.0%
death-coded share
Cattle
most-reported species
5
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
9
Deaths Reported
75.0%
Death Rate

Active Ingredients

Extended Release Trenbolone Acetate And Estradiol Implant

Administration Routes

UnknownOther

Species Affected

Cattle 12

Most Affected Breeds

Cattle (unknown) 3
Holstein-Friesian also known as Holstein 3
Cattle (other) 3
Crossbred Bovine/Cattle 2
Mixed (Cattle) 1

Most Reported Reactions

Death 5
Behavioural disorder NOS 5
Pneumonia 4
Respiratory tract disorder NOS 4
Digestive tract disorder NOS 4
Lameness 4
Ruminal bloat 3
Calculi 3
Found dead 3
Necropsy performed 3
Lung oedema 3
Bronchopneumonia 3

Outcome Breakdown

Died
9 (50.0%)
Outcome Unknown
7 (38.9%)
Euthanized
2 (11.1%)

Extended Release Trenbolone Acetate And Estradiol Implant Adverse Event Insights

12 reports name Extended Release Trenbolone Acetate And Estradiol Implant; 9 recorded a death outcome (75.0% of reported events, not a population-level mortality rate). Active ingredient: Extended Release Trenbolone Acetate And Estradiol Implant. Administration routes: Unknown, Other.

By species: Cattle (12 reports). By breed: Cattle (unknown) (3), Holstein-Friesian also known as Holstein (3), Cattle (other) (3).

Leading clinical signs: Death (5), Behavioural disorder NOS (5), Pneumonia (4), Respiratory tract disorder NOS (4). Outcome, 18 coded reports: Died leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.