Drug profile

The FDA adverse-event record for Escherichia Coli J5,97040,Killed

11 FDA reports name Escherichia Coli J5,97040,Killed, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2447 of 2,679
by report volume (all drugs)
11
adverse-event reports
81.8%
death-coded share
Cattle
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Escherichia Coli J5,97040,Killed ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Escherichia Coli J5,97040,Killed has 11 reports now versus 10 in that prior snapshot: 1 more (10.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−8.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Escherichia Coli J5,97040,Killed changes

Signature read: Escherichia Coli J5,97040,Killed's 81.8% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
9
Deaths Reported
81.8%
Death-coded share of reports

Active Ingredients

Escherichia Coli J5,97040,Killed

Administration Routes

UnknownSubcutaneousIntramuscular

Species Affected

Cattle 11

Most Affected Breeds

Holstein-Friesian also known as Holstein 6
Cattle (other) 4
Jersey 1

Most Reported Reactions

Death 7
Lack of efficacy (bacteria) - NOS 5
NT - Abnormal necropsy finding NOS 3
CULTURE/TITER DATA ABNORMAL 3
Death by euthanasia 2
Necropsy performed 2
Recumbency 1
Injection site inflammation 1
Injection site stiffness 1
Unrelated death 1
Lack of efficacy (bacteria NOS) 1
Lying down 1

Outcome Breakdown

Died
8 (44.4%)
Recovered/Normal
4 (22.2%)
Outcome Unknown
4 (22.2%)
Euthanized
2 (11.1%)

Escherichia Coli J5,97040,Killed: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Escherichia Coli J5,97040,Killed (#2447 of 2,679 by report volume); death-coded 81.8%. PlainBreed drug row · death-coded share stamp 81.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →