Drug profile

The FDA adverse-event record for Enalapril 2.5Mg

11 FDA reports name Enalapril 2.5Mg, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2446 of 2,679
by report volume (all drugs)
11
adverse-event reports
9.1%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Enalapril 2.5Mg ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Enalapril 2.5Mg has 11 reports now versus 10 in that prior snapshot: 1 more (10.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Enalapril 2.5Mg changes

Signature read: 11 reports place Enalapril 2.5Mg in the lower third of FDA AER volume (#2446 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
1
Deaths Reported
9.1%
Death-coded share of reports

Active Ingredients

Enalapril 2.5Mg

Administration Routes

OralUnknown

Species Affected

Cat 7
Dog 4

Most Affected Breeds

Maine Coon 4
Sphynx 3
Terrier - Yorkshire 2
Spaniel - King Charles Cavalier 1
Spaniel - Cocker American 1

Most Reported Reactions

Diarrhoea 2
Abnormal stool colouration 2
Emesis (multiple) 2
Increased respiratory rate 2
Weight loss 2
Vomiting 2
Ataxia 1
Not defecating 1
Not eating 1
Congestive heart failure 1
Decreased appetite 1
Partial adipsia 1

Outcome Breakdown

Outcome Unknown
6 (54.5%)
Recovered/Normal
3 (27.3%)
Ongoing
1 (9.1%)
Euthanized
1 (9.1%)

Enalapril 2.5Mg: lower report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Enalapril 2.5Mg (#2446 of 2,679 by report volume); death-coded 9.1%. PlainBreed drug row · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →