Drug profile

The FDA adverse-event record for Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
25.0%
death-coded share
Horse
most-reported species
4
Fever - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
4
Deaths Reported
25.0%
Death Rate

Active Ingredients

Eastern Encephalomyelitis Virus, Killed VirusTetanus ToxoidWest Nile Virus, Killed VirusWestern Encephalomyelitis Virus, Killed Virus

Administration Routes

IntramuscularUnknownSubcutaneousTransplacental

Species Affected

Horse 16

Most Affected Breeds

Quarter Horse 5
Arab 2
Horse (unknown) 2
Warmblood - Dutch 2
Belgian Draft, also called Brabant or Brabants trekpaard 1
Morgan 1
Pony (unspecified) 1
Miniature 1
Paint 1

Most Reported Reactions

Fever 4
Colic 3
Anorexia 3
Death by euthanasia 2
Tachycardia 2
Ataxia 2
Recumbency 2
Depression 2
Not eating 2
Death 2
Injection site swelling 2
Breathing difficulty 2

Outcome Breakdown

Recovered/Normal
6 (37.5%)
Ongoing
4 (25.0%)
Euthanized
2 (12.5%)
Died
2 (12.5%)
Outcome Unknown
1 (6.3%)
Recovered with Sequela
1 (6.3%)

Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus Adverse Event Insights

16 reports name Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus; 4 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). Active ingredients: Eastern Encephalomyelitis Virus, Killed Virus, Tetanus Toxoid, West Nile Virus, Killed Virus, Western Encephalomyelitis Virus, Killed Virus. Administration routes: Intramuscular, Unknown, Subcutaneous, Transplacental.

By species: Horse (16 reports). By breed: Quarter Horse (5), Arab (2), Horse (unknown) (2).

Leading clinical signs: Fever (4), Colic (3), Anorexia (3), Death by euthanasia (2). Outcome, 16 coded reports: Recovered/Normal leads at 37.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.