Drug profile

The FDA adverse-event record for Drontal Plus

34 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Drontal Plus. See the species affected, top reactions, and outcomes below.

34
adverse-event reports
8.8%
death-coded share
Dog
most-reported species
8
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
34
Total Reports
3
Deaths Reported
8.8%
Death Rate

Active Ingredients

Drontal Plus

Administration Routes

OralUnknown

Species Affected

Dog 32
Cat 2

Most Affected Breeds

Greyhound 3
Terrier (unspecified) 2
Pug 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Shepherd Dog - German 2
Crossbred Canine/dog 2
Spaniel - King Charles Cavalier 2
Coton de Tuléar 1
Cat (other) 1
Boxer (German Boxer) 1

Most Reported Reactions

Vomiting 8
Lack of efficacy (endoparasite) - hookworm 8
Ataxia 4
Seizure NOS 4
Diarrhoea 4
Lack of efficacy (endoparasite) - NOS 3
Anorexia 3
Lack of efficacy (endoparasite) - tapeworm 3
Nystagmus 2
Lack of efficacy (endoparasite) - whipworm 2
Loose stool 2
Abnormal posture NOS 2

Outcome Breakdown

Ongoing
26 (76.5%)
Recovered/Normal
5 (14.7%)
Died
2 (5.9%)
Euthanized
1 (2.9%)

Drontal Plus Adverse Event Insights

34 reports name Drontal Plus; 3 recorded a death outcome (8.8% of reported events, not a population-level mortality rate). Active ingredient: Drontal Plus. Administration routes: Oral, Unknown.

By species: Dog (32 reports), Cat (2 reports). By breed: Greyhound (3), Terrier (unspecified) (2), Pug (2).

Leading clinical signs: Vomiting (8), Lack of efficacy (endoparasite) - hookworm (8), Ataxia (4), Seizure NOS (4). Outcome, 34 coded reports: Ongoing leads at 76.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.