Drug profile

The FDA adverse-event record for Doxapram Hcl

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Doxapram Hcl. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
64.0%
death-coded share
Dog
most-reported species
16
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
16
Deaths Reported
64.0%
Death Rate

Active Ingredients

Doxapram Hcl

Administration Routes

UnknownIntravenousOtherSubcutaneous

Species Affected

Dog 13
Cat 11
Snake 1

Most Affected Breeds

Domestic Shorthair 6
Shih Tzu 2
Spaniel - King Charles Cavalier 2
Siberian Husky 1
Retriever - Labrador 1
Domestic Mediumhair 1
Domestic Longhair 1
Terrier - Rat 1
Scottish Fold Longhair 1
Bloodhound 1

Most Reported Reactions

Death 16
Cardiac arrest 10
Respiratory arrest 9
Lateral recumbency 5
Cyanosis 5
Seizure NOS 4
Hypothermia 4
Other abnormal test result NOS 3
Vocalisation 3
Bradycardia 3
Dyspnoea 2
Abnormal radiograph finding 2

Outcome Breakdown

Died
16 (64.0%)
Recovered/Normal
5 (20.0%)
Ongoing
4 (16.0%)

Doxapram Hcl Adverse Event Insights

25 reports name Doxapram Hcl; 16 recorded a death outcome (64.0% of reported events, not a population-level mortality rate). Active ingredient: Doxapram Hcl. Administration routes: Unknown, Intravenous, Other, Subcutaneous.

By species: Dog (13 reports), Cat (11 reports), Snake (1 reports). By breed: Domestic Shorthair (6), Shih Tzu (2), Spaniel - King Charles Cavalier (2).

Leading clinical signs: Death (16), Cardiac arrest (10), Respiratory arrest (9), Lateral recumbency (5). Outcome, 25 coded reports: Died leads at 64.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.